Description

Overview:

(This case study was added to OER Commons as one of a batch of over 700. It has relevant information which may include medical imagery, lab results, and history where relevant. A link to the final diagnosis can be found at the end of the case study for review. The first paragraph of the case study -- typically, but not always the clinical presentation -- is provided below.)

A 36-year-old man presented with a large nasal tumor following a long history of multiple meningiomas. At the age of 13, the patient underwent surgical resection and received a single course of radiation therapy for a left optic meningioma. He did well until age 33, when he was found to have multiple meningiomas in three new locations: falcine (Figure 1a), right petroclival and right anterior foramen magnum. These were surgically resected but no additional radiation was administered. Three years later, the patient presented with nasal symptoms, headaches, and seizures. Imaging studies revealed a large mass with intracranial and nasopharyngeal component measuring 4.1 x 5.4 x 6.8 cm in greatest dimensions and causing right frontal lobe compression (Figures 1b and 1c). A systemic workup, including PET CT, for other malignancies was unremarkable. A two-stage surgical resection was performed. The mass was initially biopsied by transsphenoidal endoscopic approach and then partially resected by bifrontal craniotomy, frontal sinus obliteration, en bloc ethmoidectomy, and nasal cavity resection.

Subject:

Health, Medicine and Nursing, Education, Life Science

Level:

College / Upper Division, Graduate / Professional, Career / Technical

Material Type:

Case Study, Diagram/Illustration

Author:

Don-John Summerlin, Eyas M Hattab, Isaac C Wu, James C Miller, Marwah M Abdulkader

Provider:

University of Pittsburgh School of Medicine

Provider Set:

Department of Pathology

Date Added:

08/01/2022