Description

Overview:

Mature B cells that undergo stimulation by an antigen undergo class switching, and differentiate into either plasma or memory cells. In the paracortex region of the lymph node binding to MHC II in the presence of IL-4 produced by the CD4+ T cells (TH2 type) causes the B cells to differentiate; most will become plasma cells, however a small number will become memory cells. Follicular dendritic cells present in the germinal centers of peripheral lymphoid organs can absorb intact antigen onto their surface to present to B cells to stimulate differentiation.

Subject:

Life Science

Level:

Graduate / Professional, Career / Technical

Material Type:

Diagram/Illustration, Reading

Provider:

WikiVet

Provider Set:

Blood

Date Added:

02/11/2015